中山大学孙逸仙纪念医院
逸仙优秀青年医学人才
培养计划
作者:人力资源部   发布时间:2019-11-11 点击数:162
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陈凯

基本情况

姓名:陈凯

性别:
职称:副主任医师

行政职务:

学科专业:乳腺肿瘤中心

导师资格:硕士生导师

研究方向:乳腺肿瘤的基础与临床

电子邮箱:ckaichen@126.com

 

 

个人简介

陈凯,广东省医疗行业协会乳腺专科管理分会副主任委员,早期乳腺癌保乳手术中国专家共识(2019版)编写专家组成员。主持国家自然科学基金青年项目,广东省自然科学基金博士启动项目。第一或通讯作者发表SCI文章28篇,协作者17篇。《乳腺癌保乳治疗学》副主编(人民卫生出版社),《乳腺癌保乳治疗苏逢锡2017观点》副主编(科学技术文献出版社)。

 

 

重要学术研究成果与贡献

一、主持科研项目

1         国家自然科学基金青年项目《miR-29c在乳腺癌Lapatinib耐药中的作用及机制研究》,批准编号81402201, 批准金额23万元。项目起止年月2015-12017-12. 项目负责人

2         广东省自然科学基金博士启动项目《miRNA在乳腺癌靶向耐药中的作用及机制研究》,编号2014A030310070,批准金额10万元。项目起止年月2015-12018-01. 项目负责人

3        中山大学5010临床研究青年培育项目《非哺乳期肉芽肿性乳腺炎乳管冲洗对比激素治疗:多中心、随机对照、开放标签、非劣效性临床试验》,批准金额10万元,项目起止年月2019-12021-01.,项目负责人。

二、代表性论著

1Chen, K.#, L. Zhu#, L. Chen#, Q. Li, S. Li, N. Qiu, Y. Yang, F. Su* and E. Song* (2019). Circumferential Shaving of the Cavity in Breast-Conserving Surgery: A Randomized Controlled Trial. Ann. Surg. Oncol., Springer International Publishing. 307: 467-468.

 

2Chen, K.#, L. Zhu#, T. Hu, C. Tan, J. Zhang, M. Zeng, S. Li* and E. Song*(2019). Ductal Lavage for Patients With Nonlactational Mastitis: A Single-Arm, Proof-of-Concept Trial. J. Surg. Res.235: 440-446.

 

3Lu, Y.#, Y. Chen#, L. Zhu#, P. Cartwright, E. Song*, L. Jacobs* and K. Chen* (2019). Local Recurrence of Benign, Borderline, and Malignant Phyllodes Tumors of the Breast: A Systematic Review and Meta-analysis. Ann. Surg. Oncol., Springer International Publishing. 90: 342-313.

 

4Zhu, L. and K. Chen (2019). Clinicopathological features, treatment patterns, and prognosis of squamous cell carcinoma of the breast: an NCDB analysis. BMC Cancer, BioMed Central. 19: 867.

 

5Zhu, L.#, K. Chen, L. K*. Jacobs* and R. Aft (2018). Axillary Lymphadenectomy in Sentinel Lymph Node-Positive Breast Cancer. Ann. Surg. Oncol.25: 28-31.

 

6Chen, K#., Z. Pan#, L. Zhu, T. Hu, M. Peng, W. Jia, F. Su, S. Li* and E. Song* (2018). Comparison of breast-conserving surgery and mastectomy in early breast cancer using observational data revisited: a propensity score-matched analysis. Sci China Life Sci, Science China Press: 1-9.

 

7Chen, K.#, J. Liu#, S. Li and L. Jacobs (2017). Development of nomograms to predict axillary lymph node status in breast cancer patients. BMC Cancer, BioMed Central. 17: 561.

 

8Zhao, J.*, Y. Wang*, Z. Lao, S. Liang, J. Hou, Y. Yu, H. Yao, N. You# and K. Chen# (2017). Prognostic immune-related gene models for breast cancer: a pooled analysis. Onco Targets Ther, Dove Press. 10: 4423-4433.

 

9Ouyang, Q.#, S. Li#, C. Tan, Y. Zeng, L. Zhu, E. Song, K. Chen* and F. Su* (2016). Benign Phyllodes Tumor of the Breast Diagnosed After Ultrasound-Guided Vacuum-Assisted Biopsy: Surgical Excision or Wait-and-Watch? Ann. Surg. Oncol., Springer International Publishing. 23: 1129-1134.

 

10Ouyang, Q.#, L. Zhu#, K. Chen* and F. Su* (2015). Effect of Implant vs. Tissue Reconstruction on Cancer Specific Survival Varies by Axillary Lymph Node Status in Breast Cancer Patients. PLoS ONE. 10: e0118161.

 

11Chen, K., F. Su and L. K. Jacobs (2015). A Nomogram to Predict the Benefit of Radiation Therapy After Breast-Conserving Surgery in Elderly Patients with Stage I &amp; ER-Negative, or Stage II/III Disease. Ann. Surg. Oncol.22: 3497-3503.

 

12Chen, K.#, X. Zhang#, H. Deng, L. Zhu, F. Su, W. Jia* and X. Deng* (2014). Clinical predictive models for chemotherapy-induced febrile neutropenia in breast cancer patients: a validation study. PLoS ONE, Public Library of Science. 9: e96413.

 

13Chen, K., L. Zhu, E. Song and F. Su (2013). Re: international multicenter tool to predict the risk of nonsentinel node metastases in breast cancer. J. Natl. Cancer Inst., Oxford University Press. 105: 1513-1514.

 

14Chen, K.#, Y. Zeng#, H. Jia, W. Jia, H. Yang, N. Rao, E. Song, C. E. Cox* and F. Su* (2012). Clinical outcomes of breast-conserving surgery in patients using a modified method for cavity margin assessment. Ann. Surg. Oncol., Springer-Verlag. 19: 3386-3394.

 

15Chen, K.#, L. Zhu#, W. Jia, N. Rao, M. Fan, H. Huang, Q. Shan, J. Han, E. Song, Y. Zeng and F. Su* (2012). Validation and comparison of models to predict non-sentinel lymph node metastasis in breast cancer patients. Cancer Sci., Blackwell Publishing Ltd. 103: 274-281.

 

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三、发明专利

申请中

 

学术论著与教材

-人民卫生出版社<<乳腺癌保乳治疗学>>副主编

-科学技术文献出版社<<乳腺癌保乳治疗>>苏逢锡2017观点>>副主编

-科学技术文献出版社《乳腺癌乳房重建宋尔卫2017观点》编者

-Wolters Kluwer Health出版社《Operative Standards for Cancer Surgery: Volume I: Breast, Lung, Pancreas, Colon》编者

获奖及荣誉

-2011年美国SABCSAACR International Scholar-in-Training Grant

-2015年韩国GBCCSusan G. Komen Breast Cancer Foundation Scholarship

2016年中山大学孙逸仙纪念医院逸仙医学人才项目

学术兼职

-广东省医疗行业协会乳腺专科管理分会副主任委员

-中国抗癌协会肿瘤标志专业委员会委员

-广东省抗癌协会乳腺癌专业委员会委员

-广东省医师协会乳腺专科医师分会委员

 

 

 

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