FACULTY

Chen Weiliang

2012-12-18 00:53
DDS & MD
Professor & Chief Surgeon of Oral and Maxillofacial Surgery
Ph.D. Candidate Supervisor
Director of Stomatological Department, SYSH
Director of Cranio-maxillofacial Surgery Centre, SYSU

Clinical Focus
Diagnosis and treatment of jaw cysts, branchial cyst, pleomorphic adenoma, ameloblastoma, tongue cancer, gingival cancer, buccal cancer, palate cancer, lingual root cancer;

Therapy of oral-maxillofacial injuries;

Treatment of oral-maxillofacial infections;

Reconstructive surgery of congenital oral-maxillofacial malformation (such as cleft lip and palate, deformation of the jaws) and acquired oral-maxillofacial deformity (such as traumatic scar and defects);

Treatment of mandibular protrusion and retrusion and diagnosis and treatment of pain in the oral and craniofacial regions.

 

Research Interests
Prof. Chen Weiliang has carried out scientific research at molecular level on oral and maxillofacial-head and neck tumors including benign and malignant tumors. He is an expert in surgical oncology, reconstruction of defects of soft and hard tissue, chemotherapy for middle-and-late-stage oral cancer, gene-targeting therapy, and immunotherapy. He has also been working on super-selective embolization, radiation, sclerotherapy, radionuclide therapy and cryotherapy for hemangioma, lymphangioma, and vascular malformation.

 

Academic Achievements
Prof. Chen Weiliang has published more than 100 pieces of research papers, of which 70 are peer reviewed publications (SCI cited paper). Since 2003, he has been chairing the Senior Workshop on Preventing and Treating Oral-maxillofacial-head and neck Tumor, which is one of the National Continuous Education Programs in China. Prof. Chen Weiliang has tutored more than 30 masters and more than 20 PhD and postdoctoral students since 1998. He has also won supports from 15 research programs of provincial and national level (grants worth more than two million RMB).

 

Education/ Training
Prof. Chen Weiliang graduated from Sun Yat-sen University of Medical Sciences in 1983. After graduation, he spent 5 years in taking the residency and M.D. training courses and 7 years in practicing oral and maxillofacial surgeries. In 1998, He moved to the US. as a visiting professor at University of California (UCLA) for research and surgeries training. In 2003, He was assigned to the Department of Plastic and Maxillofacial Surgery in Royal Children’s Hospital of Melbourne, Australia. Two years later, he went to the University of California, Berkely, to study the management of technology program. At the same year, Prof. Chen Weiliang was granted h-EMBA by Lingnan School of Sun Yat-sen University.
 

Social Responsibility
Chairman of Maxillofacial-Head and Neck Surgery Committee, Guangdong Medical Association
Editorial Member of China Journal of Oral and Maxillofacial Surgery
Member of International Association of Oral and Maxillofacial Surgeons
Member of International Association of Oral Cancer


Representative Publications

1. Wang L, Chen WL(Corresponding Author). Surgical excision of sialoblastoma in the parotid gland in newborn. Int J Pediatr Otorhinolaryngol. 2013;77(8):1268-71.
 
2. Chen WL, et al. Osteotomy in the vertical ramus outside the   mandibular foramen for tumours in the parapharyngeal space. J Craniomaxillofac Surg. 2013 Jun 18. [Epub ahead of print]
 
3. Chen WL, et al. Functional hemitongue reconstruction  using innervated supraclavicular  fasciocutaneous island flaps with the cervical plexus and reinnervated supraclavicular fasciocutaneous island flaps with neurorrhaphy of the cervical plexus and lingual nerve. Head Neck. 2013 Jun 1 [Epub ahead of print]
 
4. Chen WL, et al. Percutaneous sclerotherapy of sialoceles after parotidectomy with fibrin glue,  OK-432, and bleomycin. Br J Oral Maxillofac Surg. 2013 Apr 29. [Epub ahead of print]
 
5. Wu H, Chen WL(Corresponding Author). Functional Reconstruction With an Extended Supraclavicular Fasciocutaneous Island Flap Following Ablation of Advanced Oropharyngeal Cancer. J Craniofac Surg. 2012;23(6):1668-71.
 
6. You YH, Chen WL(Corresponding Author). Closure of large oropharyngocutaneous fistulas using a folded extensive supraclavicular fasciocutaneous island flap J Oral Maxillofac Surg Med Pathol,2012.09.012 ARTICLE IN PRESS
 
7. Wei FH, Chen WL(Corresponding Author). Contralateral Full-thickness Retroangular Flap for the Reconstruction of Midfacial Through-and-through Defects Following Skin Cancer Ablation. Chin J Dent Res. 2012;15(1):21-4.
 
8. Li JS, Chen WL(Corresponding Author). Extracapsular dissection of pleomorphic adenoma of the parotid gland through minimal preauricular and retroauricular incisions in children. J Craniofac Surg. 2012;23(3):661-3.
 
9. Li HG, Han JJ, Huang ZQ, Wang L, Chen WL(Corresponding Author). IMP3 Is a Novel Biomarker to Predict Metastasis and Prognosis of Tongue Squamous Cell Carcinoma. J Craniofac Surg. 2011;22(6):2022-5.
 
10. Chen WL, et al. Double mental neurovascular v-y island advancement flaps combined with tongue flaps for functionally reconstructing total lower-lip defects. J Craniofac Surg. 2012;23(1):181-3.
 
11. Fan S, Tang QL, Lin YJ, Chen WL(Corresponding Author). A review of clinical and histological parameters associated with contralateral neck metastases in oral squamous cell carcinoma. Int J Oral Sci. 2011;3(4):180-91.
 
12. Chen WL, et al. Reconstruction of Major Full Cheek Defects With Combined Extensive Pedicled Supraclavicular Fasciocutaneous Island Flaps and Extended Vertical Lower Trapezius Island Myocutaneous Flaps After Ablation of Advanced Oral Cancer. J Oral Maxillofac Surg. 2012;70(5):1224-31.
 
13. You YH, Chen WL(Corresponding Author). SMAS fold flap and allograft dermal matrix repairing parotid bed following parotidectomy to prevent facial deformity and Frey's syndrome. Asian J Oral Maxillofac Surg. 2012, 24(1):18-22
 
14. Tang QL, Chen WL(Corresponding Author). Expression and significance of Cyr61 in distant metastasis cells of human primary salivary adenoid cystic carcinoma Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(2):228-36.
 
15. Chai Q, Chen WL(Corresponding Author). Preliminary Experiences in Treating Infantile Hemangioma With Propranolol. Ann Plast Surg. 2011 May 27. [Epub ahead of print]
 
16. Chen WL, et al. Maxillary Functional Reconstruction Using a Reverse Facial Artery–Submental Artery Mandibular Osteomuscular Flap with Dental Implants. J Oral Maxillofac Surg, 2011;69(11):2909-14.
 
17. Tang QL, Fan S, Li HG, Chen WL(Corresponding Author). Expression of Cyr61 in primary salivary adenoid cystic carcinoma and its relation to Ki-67 and prognosis. Oral Oncol. 2011;47(5):365-70.
 
18. Zhen Y, Wang JG, Tao D, Wang HJ, Chen WL(Corresponding Author). Efficacy survey of swallowing function and quality of life in response to therapeutic intervention following rehabilitation treatment in dysphagic tongue cancer patients. Eur J Oncol Nurs. 2012;16(1):54-8.
 
19. Wang YY, Chen WL(Corresponding Author). Expression of the membrane-cytoskeletal linker Ezrin in salivary gland adenoid cystic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(1):96-104.
 
20. Chen WL, et al. Percutaneous sclerotherapy of massive macrocystic lymphatic malformations of the face and neck using fibrin glue with OK-432 and bleomycin. Int J Oral Maxillofac Surg. 2011;40(6):572-6.
 
21. Fan S, Chen WL(Corresponding Author). Concerns about anesthetizing palatal tissues. J Oral Maxillofac Surg. 2011;69(2):574.
 
22. Chen WL, et al. Mandible reconstructed with mandibular osteomuscular and facial-cervico-pectoral flap. Asian J Oral Maxillofac Surg. 2011;(23):69-72
 
23. Chen WL, et al. Use of the contralateral retroangular island flap for reconstructing midfacial defects after skin cancer ablation. Head Neck. 2011;33(12):1765-8.
 
24. Wang JG, Chen WL(Corresponding Author). Reverse facial artery-submental artery deepithelialised submental island flap to reconstruct maxillary defects following cancer ablation. J Craniomaxillofac Surg. 2011;39(7):499-502.
 
25. Huang ZQ, Chen WL(Corresponding Author). Extracellular matrix metalloproteinase inducer expression in salivary gland tumors: a correlation with microvessel density. J Craniofac Surg. 2010;21(6):1855-60.
 
26. Chen WL, Zhang DM, Yang ZH, Huang ZQ, Wang JG, Zhang B, Li JS. Extended supraclavicular fasciocutaneous island flap based on the transverse cervical artery for head and neck reconstruction after cancer ablation. J Oral Maxillofac Surg. 2010;68(10):2422-30.
 
27. Chen WL, et al. A pedicled mandibular osteomuscular flap for reconstructing composite mandibular defects. Oral Surg. 2010;3(1):16-21.
 
28. Chen WL, et al. Reconstruction of large defects of the neck using an extended vertical lower trapezius island myocutaneous flap following salvage surgery for neck recurrence of oral carcinoma. J Plast Reconstr Aesthet Surg. 2011;64(3):319-22.
 
29. Zhang B, Wang JG, Chen WL(Corresponding Author). Reverse facial-submental artery island flap for reconstruction of oropharyngeal defects following middle and advanced-stage carcinoma ablation. Br J Oral Maxillofac Surg. 2011;49(3):194-7
 
30. You YH, Chen WL(Corresponding Author). The feasibility of facial-submental artery island myocutaneous flaps for reconstructing defects of the oral floor following cancer ablation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(6):e12-6.
 
31. Chen WL, et al. Percutaneous sclerotherapy of juvenile nasopharyngeal angiofibroma using fibrin glue combined with OK-432 and bleomycin. Int J Pediatr Otorhinolaryngol. 2010;74(4):422-425.
 
32. Chen WL, et al. Facial Contour Reconstruction After Benign Tumor Ablation Using Reverse Facial-Submental Artery Deepithelialized Submental Island Flaps. J Craniofac Surg. 2010;21(1):83-86.
 
33.You YH, Chen WL(Corresponding Author). Reverse facial-submental artery island flap for the reconstruction of maxillary defects after cancer ablation. J Craniofac Surg. 2009;20(6):2217-20
 
34. Fan S, Chen WL(Corresponding Author), et al. Anesthetic efficacy of inferior alveolar nerve block plus buccal infiltration or periodontal ligament injections with articaine in patients with irreversible pulpitis in the mandibular first molar. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108(5):e89-93.
 
35. Chen WL, et al. Percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK-432 and pingyangmycin. Head Neck. 2010,32(4):467-472.
 
36. Li HG, Li JS, Chen WL(Corresponding Author), et al. Prognostic significance of erythropoietin and erythropoietin receptor in tongue squamous cell carcinoma. Br J Oral Maxillofac Surg. Br J Oral Maxillofac Surg. 2009;47(6):470-5. Epub 2009 Jun 25.
 
37. Chen WL, et al. Submental flap for reconstructing tongue defect with V-Y advancement flap for repairing submental defect. Otolaryngol Head Neck Surg. 2009;141(2):202-206.
 
38. Chen WL, et al. A multidisciplinary approach to treating maxillofacial arteriovenous malformations in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108(1):41-47.
 
39. Chen WL, et al. Surgical excision of cervicofacial giant macrocystic lymphatic malformations in infants and children. Int J Pediatr Otorhinolaryngol. 2009;73(6):833-7.
 
40. Yan L, Chen WL(Corresponding Author), et al. Inhibition of VEGF expression in tongue squamous cancer cells via RNA interference silencing of iNOS gene. Int J Oral Maxillofac Surg. 2009,38(4):369-373.
 
41. Li JS, Chen WL(Corresponding Author), et al. Pediatric Mandibular Reconstruction After Benign Tumor Ablation Using a Vascularized Fibular Flap. J Craniofac Surg. 2009,20(2):431-434
 
42. Chen WL, et al. The trapezius osteomyocutaneous island flap for reconstructing hemimandibular and oral defects following the ablation of advanced oral malignant tumors. J Craniomaxillofac Surg. 2009,37(2):91-95.
 
43. Chen WL, et al. Transplantation of a reverse facial artery pedicled submandibular gland in a dog. Int J Oral Maxillofac Surg. 2008;37(11):1054-8.
 
44. Chen WL, et al. Reverse facial artery-submental artery mandibular osteomuscular flap for the reconstruction of maxillary defects following the removal of benign tumors. Head Neck. 2009,31(6):725-731.
 
45. Fan S, Chen WL﹡, et al. Comparison of the efficiencies of permanent maxillary tooth removal performed with single buccal infiltration versus routine buccal and palatal injection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009,107(3): 359-363
 
46. Chen WL, et al. Liquid nitrogen cryotherapy of lip mucosa hemangiomas under inhalation general anesthesia with sevoflurane in early infancy. Ann Plast Surg.2009;62(2):154-7
 
47. Chen WL, et al. Removal of second branchial cleft cysts using a retroauricular approach. Head Neck. 2009;31(5):695-698.
 
48. Chen WL, et al. Expression of Inducible Nitric Oxide Synthase and Vascular Endothelial Growth Factor in Ameloblastoma. J Craniofac Surg. 2009;20(1):171-175.
 
49. Chen WL, et al. Reconstruction with Extended Vertical Lower Trapezius Island Myocutaneous Flap for Total Glossectomy. Chin J Dental Research, 2008,11(1),42-46.
 
50. Chen WL, et al. Removal of the submandibular gland using a combined retroauricular and transoral approach. J Oral Maxillofac Surg. 2009;67(3):522-7.
 
51. Chen W, et al. SMAS fold flap and ADM repair of the parotid bed following removal of   parotid haemangiomas via pre- and retroauricular incisions to improve cosmetic outcome and prevent Frey's syndrome. J Plast Reconstr Aesthet Surg. 2008;61(8):893-898.
 
52. Chen WL, et al. Effect of using RNA interference to alter iNOS gene expression on the proliferation of tongue squamous cell carcinoma cell line Tca8113. Br J Oral Maxillofac Surg. 2008,46(6):435-438.
 
53. Chen WL, et al. Expression and significance of hypoxemia-inducible factor-1alpha in osteosarcoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(2):254-257.
 
54. Chen WL, et al. Reconstruction of the tongue using an extended vertical lower trapezius island myocutaneous flap after removal of advanced tongue cancer. Br J Oral Maxillofac Surg. 2008,46(5):379-382.
 
55. Chen WL, et al. Two submental island flaps for reconstructing oral and maxillofacial defects following cancer ablation. J Oral Maxillofac Surg. 2008;66(6):1145-56.
 
56. Chen WL, et al. Extended vertical lower trapezius island myocutaneous flap for repairing extensive oropharyngeal defects. J Oral Maxillofac Surg. 2009;67(6):1349-53.
 
57. Chen WL, et al. A pilot study on combination compartmentalization and sclerotherapy for the treatment of massive venous malformations of the face and neck. J Plast Reconstr Aesthet Surg. 2008;61(12):1486-92.
 
58. Chen WL, et al. Pedicled Mandibular Osteomuscular Flap for Zygomatic Reconstruction through a Modified Weber-Ferguson Incision. J Craniofac Surg. 2008; 19(1):235-240.
 
59. Chen WL, et al. Expression and pathological relevance of inducible nitric oxide synthase in osteosarcoma of the jaws. Int J Oral Maxillofac Surg. 2007;36(6):541-4.
 
60. Chen WL, et al. Extended vertical lower trapezius island myocutaneous flap in reconstruction of oral and maxillofacial defects after salvage surgery for recurrent oral carcinoma. J Oral Maxillofac Surg. 2007, 65(2):205-11.
 
61. Chen W, et al. Reconstruction of full cheek defects with combined temporalis myofacial flaps and  facial-cervico-pectroral flaps. Oral Surg Oral Med, Oral Pathol Oral Radiol Endod. 2007, 103(1): e10-e15.
 
62. Chen WL, et al. Extended vertical lower trapezius lsland myocutaneous flap for reconstruction of cranio-maxillofacial defects. Int J Oral Maxillofac Surg. 2007, 36(2):165-70.
 
63. Chen WL, et al. Recurrent ameloblastoma of the anterior skull base: three cases treated by radical resections. J Craniomaxillofac Surg. 2006;34(7):412-4.
 
64. Chen WL, et al. Comprehensive treatment of arteriovenous malformations in the oral and maxillofacial region. J Oral Maxillofac Surg, 2005,63(10):1484-1488 0278-2391.

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