Zhang Shaoling

2012-11-25 23:00
M.D. & Ph.D.
Professor of Endocrinology
Doctoral Supervisor
Endocrinology Department

Clinical Focus
Prof. Zhang Shaoling has been working at the clinical frontline for more than 20 years. She is especially good at the diagnosis and treatment of diabetes, thyroid diseases, secondary hypertension and adrenal gland disorders.


Research Interests
Prof. Zhang Shaoling works to improve the protection of ovarian function. She has also carried on the study of endometrial receptivity and non-invasive assessment of embryo viability.


Academic Achievements
Prof. Zhang Shaoling has published more than 50 pieces of research papers with 10 of them as SCI papers. She has also led and participated more than 10 research projects of national and provincial level. Her studies on diabetes have won the first prize of the 2000 Guangdong Medical Science and Technology award of Progress and the third prize of the 2000 Guangdong Scientific and Technological Progress Award.


1990,  Bachelor’s Degree,  Sun Yat- Sen University of Medical Sciences
1996,  Master’s Degree,  Sun Yat-Sen University of Medical Sciences
2004,  Doctoral Degree,  Hôpital Neker
2006,  Prof. Zhang Shaoling furthered her studies on diabetes at the Medical Research Center at Kobe University in Japan


Social Responsibility
Committee Member of Endocrinology Studies, Guangdong Medical Association
Committee Expert of Guangzhou Science Expert Commission for Population and Family Planning
Member of Adrenal Gland Study Group, Endocrinology Affiliate, Chinese Medical Association


Representative Publications

1. Zhang SL, Cheng H, Fu ZZ, et al. Contribution of the absence of aspartic acid at position 57 of the HLA-DQβ chain to predisposition to insulin-dependent diabetes mellitus in a Southern Chinese population. Chin Med J 1998;111:694-697.

2. Zhang Shaoling, Penfornis A. Tiberghien P., et al. TAP2/651 gene polymorphism in DR4 positive Type 1 Diabetes in Eastern French population. Abstract/Diabetes Research and Clinical Practice. 56 suppl 1(2002)S1-S282:s88.

3. Zhang SL, Chabod J, Penfornis A, et al. TAP1 and TAP2 gene polymorphism in rheumatoid arthritis in a population in eastern France. Eur J Immunogenet. 2002 Jun;29(3):241-9.

4. LIU Pinming, ZHANG Shaoling, Francois Schiele, et al. Clinical outcome of patients with left anterior descending artery ostial lesions treated with percutaneous coronary intervention: case-matched comparison with bypass surgery. Chin Med J 2003 Jun;116(6):844-848

5. Zhang S, Penfornis A, Harraga S, Chabod J, Beurton I, Bresson-Hadni S, Tiberghien P, Kern P, Vuitton DA. Polymorphisms of TAP1 and TAP2 genes in Human Alveolar Echinococcosis. Eur J Immunogenet 2003;30(2):133-9

6. Hüe S, Mention JJ, Monteiro RC, Zhang S, Cellier C, Schmitz J, Verkarre V, Fodil N, Bahram S, Cerf-Bensussan N, Caillat-Zucman S. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity. 2004 Sep;21(3):367-377

7. Vuitton DA, Zhang SL, YANG Y, Godot V, Beurton I, Mantion G, Bresson-Hadni S. Survival strategy of echinococcosis multilocularis in the human host. Parasitology international, 2006;55:S51-S55.

8. Zhang SL, Lu WS, Yan L, Wu MC, Xu MT, Chen LH, Cheng H. Peroxisome proliferators-activated receptor-γ co-activator-1α (PGC-1α) gene polymorphisms are associated with susceptibility of type 2 diabetes and altered interaction with myocyte enhancer factor-2C (MEF2C). Chin Med J, 2007;120(21):1878-1885.

9. Zhang Y, Xu MT, Zhang SL, Cheng H. The role of GPR40 in lipoapoptosis in mouse β cell line NIT-1. Mol Endocrionology, 2007;38(6):651-661.

10. Zhang SL, Sophie H, Damien S, Vuitton DA. MICA, NKG2D and TGF-beta expression in the liver of humans with alveolar echinococcosis: new actors in the tolerance to parasites? Journal of Infectious Disease, 2008;197(9):1341-1349.

11. Zhang SL,Yin GS,Yan L, et al. physiological variability and influential factors of aldosterone and serum renin activity. Eur Heart J, 2009;30(Abstract Supplememt):1036 (SCI abstract).

12. Zhang S, Wu MC, Yan L, et al. Tolbutamide, but not repaglinide and Nateglinide, might cause beta-cell apoptosis via MAPK pathway. Diabetes, abstract A620, 2407PO, 29th  ADA, June 5-9,2009. New Orleans, LA. (SCI abstract).

13. Zhang SL, Wu LN, Wang YH, et al. Sceening pregnant women for thyroid dysfunction, 80th ATA Annual meeting, Oral 8, page 157-158, 23-27th Sep 2009, Palm Beach, Florida, USA.

14. Zhang SL, Wu LN, Cheng H, et al. Iodine status of pregnant women and role of iodine in hypothyroidism of pregnant women, 80th ATA Annual meeting, Oral 130, page 200, 23-27th Sep 2009, Palm Beach, Florida, USA

15. Zhang SL, Wu LN, Xue S, et al. Association between oxidative stress and thyroid diseases of pregnant women, 80th ATA Annual meeting,Oral 8, page 169-170, 23-27th Sep 2009, Palm Beach, Florida, USA

16. Zhang SL, Chen ZC, Qi YQ, Tang JY, Yan L, Ji LN, on behalf of CHINA RECAP study group. Predictors of glycaemic control among Chinese patients with Type 2 diabetes on oral antihyperglycemic agents: findingd from Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) study. Diabetes 2010 suppl(1):A569, 2167-PO, 70th  ADA, June 25-9,2010. Orlando, FL. (SCI abstract)

17. ZHANG Shao-ling, CHEN Zong-cun, YAN Li, CHEN Li-hong, CHENG Hua and JI Li-nong. Determinants for inadequate glycaemic control in Chinese patients with light-to-moderate type 2 diabetes on oral antidiabetic drugs alone. Chin Med J 2011;124(16):2461-2468

18. ZHANG Shaoling, YIN Guoshu, REN Meng, XU Mingtong, LI Feng, YAN Li, CHENG Hua. The serum aldosterone concentration and plasma renin activity in populations with different glucose tolerance status. Diabetes 2010 suppl(1),1804-P (71th ADA, June 24−28, 2011, in San Diego, California)

19. ZHANG Shaoling, YIN Guoshu, REN Meng, XU Mingtong, LI Feng, YAN Li, CHENG Hua. Aldosterone attenuate the insulin signal transduction in 3T3-L1 adipocyte via mineralocorticoid receptor Diabetes 2010 suppl(1), 1561-P (71th ADA, June 24−28, 2011, in San Diego, California)

20. Li Jing-yi, ZHANG Shao-ling, REN Meng, Wen Yan-ling, YAN Li, CHENG Hua. High-sodium intake aggravates myocardial injuries induced by aldosterone via oxidative stress in Sprague-Dawley rats. Acta Phamacologica Sinica. 2012, 33(3):393-400

21. Yin G, Zhang S, Yan L, et al. Effect of age on aldosterone/renin ratio (ARR) and comparison of screening accuracy of ARR plus elevated serum aldosterone concentration for primary aldosteronism screening in different age groups. Endocrine, 2012, [Epub ahead of print] (Corresponding Author)



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P.R. China